This research project investigates how repeated maternal immune challenges influence offspring development and production traits. Ewes were exposed to lipopolysaccharide (LPS), a component of Gram-negative bacteria, during key stages of follicle development. Following breeding, wool samples from their lambs were collected at 60 days of age and analyzed for quality traits. It is hypothesized that lambs born to high-dose LPS ewes will produce lower-quality wool, while those from control ewes will show the best quality, with low-dose lambs falling in between. These findings aim to understand how maternal health during breeding influences offspring performance and product quality.